Effect of treatment on Campylobacter pylori in peptic disease: a randomised prospective trial.

نویسندگان

  • H Humphreys
  • S Bourke
  • C Dooley
  • D McKenna
  • B Power
  • C T Keane
  • E C Sweeney
  • C O'Moráin
چکیده

This study investigated the effect of colloidal bismuth subcitrate and cimetidine on Campylobacter pylori in peptic disease. In 74% of 135 patients with peptic disease diagnosed at endoscopy C pylori was detected before treatment. Compared with cimetidine, colloidal bismuth subcitrate significantly decreased the incidence of C pylori after six weeks of treatment (p less than 0.001). In the colloidal bismuth subcitrate group, subsequent healing of the lesion was correlated with the clearance of C pylori, unlike in the cimetidine group. C pylori was strongly associated with the presence of histological gastritis, which was decreased by colloidal bismuth subcitrate (p less than 0.001).

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عنوان ژورنال:
  • Gut

دوره 29 3  شماره 

صفحات  -

تاریخ انتشار 1988